Scopelitis has made a career in the world of portraiture. Oils on linen or graphite on paper is a choice left to the client. She approaches her subjects from the inside out, meaning she senses the inner personality and the essence of a person before she begins to armour the portrait with flesh and bones. Constance strives for an end result that depicts the vivid life energy emmanating from her subject.

Art Historian, D.W.H. Arnold, has written, "Scopelitis is one of the few portrait artists whose work can truly be said to follow in the tradition of David, Burne-Jones, and Sargent. She is technically proficient with superb draftsmanship and command of color, but she also is able within the bounds of traditional portraiture to convey the most inexpressible 'life force' of her subjects with subtlely and beauty."